SOX2 antibody

Catalog No. ABIN7449421

This Mouse Monoclonal antibody specifically detects SOX2 in WB, IHC and ICC. It exhibits reactivity toward Human.

Quick Overview for SOX2 antibody (ABIN7449421)

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BC36

Product Details anti-SOX2 Antibody

Purpose: Mouse anti-SOX2 Monoclonal Antibody [BC36]

Immunogen: SOX2

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 using a pressure cooker is recommended for FFPE tissue sections.

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 using a pressure cooker is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Handling

Concentration: 500 μg/mL

Buffer: Phosphate Buffered Saline (PBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SOX2

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Alternative Name: SOX2

Background: Background: SRY (sex determining region Y)- box 2 (SOX2) is a transcription factor involved in embryonic development and is critical to embryonic stem cell pluripotency. Mutations in the SOX2 gene are associated with microphthalmia syndromic type 3 (MCOPS3) a condition characterized by microphthalmia or anophthalmia.

Gene ID: 6657

NCBI Accession: NP_003097

UniProt: P48431

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis